In the first step, acetoacetic ester is deprotonated and may then serve as a nucleophile and attack the alkyl halide. Right after this, the ester is then hydrolyzed to some carboxylic acid which then loses carbon dioxide through a nicely organized six-membered transaction state: Critique An assessment of oral cannabinoids https://reidtemvc.blog2news.com/33096046/detailed-notes-on-cbd-cannabidiol