Since the binding system is distinct for nucleic acids, the bound nucleic acids are purified from salts, proteins, together with other impurities by a washing step and are last but not least eluted in very low-salt Elution Buffer or PCR-quality h2o. The purified viral RNA is free of intact virus, https://magneticbeadsrnaisolation60246.uzblog.net/detailed-notes-on-isolation-of-trace-rna-43792348